Cell Line Development Service

(0 User reviews)   39   20
By cathyy smith Posted on Dec 12, 2023
In Category - Health & Fitness
James Anderson
Abstract

Cell Lines for Rare Diseases The immortalized cells have strong proliferation ability, can be passaged indefinitely, and can obtain a large number of cell resources in a shorter experimental cycle. Additionally, under the same genetic background, the stability of the experimental results can be guaranteed. A variety of cell immortalization methods have been established mainly based on the intervention of exogenous genes. Commercial cell lines including HEK293T, Hela, K562 and NIH/3T3 have been used as models for various rare diseases. Through genetic engineering, the specific genes of the cell line is mutated or overexpressed to mimic the pathogenesis of the corresponding tissues. Additionally, immortalized cells derived from the same source as the diseased tissue provide a more suitable platform for the mechanistic study of rare diseases.

There are no reviews for this PDF.

0
0 out of 5 (0 User reviews )

Add a Review

Your Rating *
There are no comments for this PDF.
You must log in to post a comment.
Log in

Related PDF